Intracystic carcinoma of the breast is a rare form of breast carcinoma. Among allmalignant breast tumors, this lesion has an incidence of 0. These neoplasms have certain characteristic imaging findings which help to differentiate these lesions from other focal breast abnormalities.
Correspondence Address: Dr. E-mail: kritichauhan25 gmail. She has an interest and special inclination towards oncopathology.
Background: Intracystic papillary carcinoma IPC is a ductal carcinoma of papillary variety that develops in a cystic space surrounded by a fibrous capsule. It is a rare clinicopathological entity, the in situ or invasive character of which is difficult to establish, particularly on biopsy. The treatment is surgical and breast conservation depends on the tumor size.
The prediction of the biological behaviour of this rare form of breast cancer and the clinical outcome showed its overall favourable prognosis; however, its consideration as a form of ductal carcinoma in situ with non-invasive nature is to be reconsidered as it has been shown to present histologically with invasion of basement membrane and even metastasis [ 2 ]. The objective of this review is to shed some light on this rare, diagnostically challenging form of breast cancer, including its radiological, histological, and molecular characteristics and its pathological classification. The final goal is to optimize the clinical management including the role of sentinel lymph node biopsy SLNBgeneral management with adjuvant radiotherapy RTmammary ductoscopy, and hormonal treatment. Intracystic papillary breast cancer IPC is best managed in the context of a multidisciplinary team.
Intracystic carcinoma of the breast refers to a breast cancer located within a cyst. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Updating… Please wait.
Papillary breast cancer is a very uncommon from of infiltrating ductal breast cancer. So, the characteristics of this cancer are a well-defined margin with many small projections. We have a newer page, with up-to-date references on types of breast cancer, including papillary breast cancer, Here.
Results: Intracystic papillary breast cancer IPC is best managed in the context of a multidisciplinary team. Conclusion: Further research is required to determine the role of adjuvant radiotherapy and endocrine therapy in IPC. Keywords: intracystic papillary breast cancer, wide local excision, ductal carcinoma in situ, mammary ductoscopy, sentinel lymph node biopsy, radiotherapy, endocrine therapy, local recurrence.
Tumor extract analysis revealed the presence of both estrogen and progesterone receptors 0. Chromatographic analysis of cystic fluid revealed two peaks of PSA, at the expected positions for free and bound serine protease. A major proportion of kDa free form was also confirmed by Western blotting analysis.
Intracystic papillary carcinoma of the breast is a rare subtype of breast cancer accounting for approximately 0. To the best of our knowledge, the occurrence of this rare subtype of breast cancer in the male is even lower with less than 20 cases reported in the English literature over the past 30 years. We report a case of an elderly Asian male with intracystic papillary breast carcinoma who initially presented with a right sided breast lump for 4 months duration and his subsequent management.
Intracystic carcinoma of the breast is a type of breast cancer with favorable prognosis where cancer arises from the cystic wall. However, it is a relatively rare disease, and no general consensus has been reached on its definition, including pathogenesis, extramural invasion, and lymph node metastasis. Six patients who underwent surgery at the Department of Surgery at Asahikawa Medical University are presented. In each patient, background factors, diagnosis, surgery, pathological diagnosis, and prognosis were investigated.